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[Analysis of the global competitive landscape in artificial intelligence medical device research].

Chen J, Pan L, Long J, Yang N, Liu F, Lu Y, Ouyang Z

pubmed logopapersJun 25 2025
The objective of this study is to map the global scientific competitive landscape in the field of artificial intelligence (AI) medical devices using scientific data. A bibliometric analysis was conducted using the Web of Science Core Collection to examine global research trends in AI-based medical devices. As of the end of 2023, a total of 55 147 relevant publications were identified worldwide, with 76.6% published between 2018 and 2024. Research in this field has primarily focused on AI-assisted medical image and physiological signal analysis. At the national level, China (17 991 publications) and the United States (14 032 publications) lead in output. China has shown a rapid increase in publication volume, with its 2023 output exceeding twice that of the U.S.; however, the U.S. maintains a higher average citation per paper (China: 16.29; U.S.: 35.99). At the institutional level, seven Chinese institutions and three U.S. institutions rank among the global top ten in terms of publication volume. At the researcher level, prominent contributors include Acharya U Rajendra, Rueckert Daniel and Tian Jie, who have extensively explored AI-assisted medical imaging. Some researchers have specialized in specific imaging applications, such as Yang Xiaofeng (AI-assisted precision radiotherapy for tumors) and Shen Dinggang (brain imaging analysis). Others, including Gao Xiaorong and Ming Dong, focus on AI-assisted physiological signal analysis. The results confirm the rapid global development of AI in the medical device field, with "AI + imaging" emerging as the most mature direction. China and the U.S. maintain absolute leadership in this area-China slightly leads in publication volume, while the U.S., having started earlier, demonstrates higher research quality. Both countries host a large number of active research teams in this domain.

Radiologist-AI workflow can be modified to reduce the risk of medical malpractice claims

Bernstein, M., Sheppard, B., Bruno, M. A., Lay, P. S., Baird, G. L.

medrxiv logopreprintJun 16 2025
BackgroundArtificial Intelligence (AI) is rapidly changing the legal landscape of radiology. Results from a previous experiment suggested that providing AI error rates can reduce perceived radiologist culpability, as judged by mock jury members (4). The current study advances this work by examining whether the radiologists behavior also impacts perceptions of liability. Methods. Participants (n=282) read about a hypothetical malpractice case where a 50-year-old who visited the Emergency Department with acute neurological symptoms received a brain CT scan to determine if bleeding was present. An AI system was used by the radiologist who interpreted imaging. The AI system correctly flagged the case as abnormal. Nonetheless, the radiologist concluded no evidence of bleeding, and the blood-thinner t-PA was administered. Participants were randomly assigned to either a 1.) single-read condition, where the radiologist interpreted the CT once after seeing AI feedback, or 2.) a double-read condition, where the radiologist interpreted the CT twice, first without AI and then with AI feedback. Participants were then told the patient suffered irreversible brain damage due to the missed brain bleed, resulting in the patient (plaintiff) suing the radiologist (defendant). Participants indicated whether the radiologist met their duty of care to the patient (yes/no). Results. Hypothetical jurors were more likely to side with the plaintiff in the single-read condition (106/142, 74.7%) than in the double-read condition (74/140, 52.9%), p=0.0002. Conclusion. This suggests that the penalty for disagreeing with correct AI can be mitigated when images are interpreted twice, or at least if a radiologist gives an interpretation before AI is used.

Patient perspectives on AI in radiology: Insights from the United Arab Emirates.

El-Sayed MZ, Rawashdeh M, Moossa A, Atfah M, Prajna B, Ali MA

pubmed logopapersJun 11 2025
Artificial intelligence (AI) enhances diagnostic accuracy, efficiency, and patient outcomes in radiology. Patient acceptance is essential for successful integration. This study examines patient perspectives on AI in radiology within the UAE, focusing on their knowledge, attitudes, and perceived barriers. Understanding these factors can address concerns, improve trust, and guide patient-centered AI implementation. The findings aim to support effective AI adoption in healthcare. A cross-sectional study involving 205 participants undergoing radiological imaging in the UAE. Data was collected through an online questionnaire, developed based on a literature review, and pre-tested for reliability and validity. Non-probability sampling methods, including convenience and snowball sampling, were employed. The questionnaire assessed participants' knowledge, attitudes, and perceived barriers regarding AI in radiology. Data was analyzed, and categorical variables were expressed as frequencies and percentages. Most participants (89.8 %) believed AI could improve diagnostic accuracy, and 87.8 % acknowledged its role in prioritizing urgent cases. However, only 22 % had direct experience with AI in radiology. While 81 % expressed comfort with AI-based technology, concerns about data security (80.5 %), lack of empathy in AI systems (82.9 %), and insufficient information about AI (85.8 %) were significant barriers. Additionally, (87.3 %) of participants were concerned about the cost of AI implementation. Despite these concerns, 86.3 % believed AI could improve the quality of radiological services, and 83.9 % were satisfied with its potential applications. UAE patients generally support AI in radiology, recognizing its potential for improved diagnostic accuracy. However, concerns about data security, empathy, and understanding of AI technologies necessitate improved patient education, transparent communication, and regulatory frameworks to foster trust and acceptance.

Curriculum check, 2025-equipping radiology residents for AI challenges of tomorrow.

Venugopal VK, Kumar A, Tan MO, Szarf G

pubmed logopapersJun 9 2025
The exponential rise in the artificial intelligence (AI) tools for medical imaging is profoundly impacting the practice of radiology. With over 1000 FDA-cleared AI algorithms now approved for clinical use-many of them designed for radiologic tasks-the responsibility lies with training institutions to ensure that radiology residents are equipped not only to use AI systems, but to critically evaluate, monitor, respond to their output in a safe, ethical manner. This review proposes a comprehensive framework to integrate AI into radiology residency curricula, targeting both essential competencies required of all residents, optional advanced skills for those interested in research or AI development. Core educational strategies include structured didactic instruction, hands-on lab exposure to commercial AI tools, case-based discussions, simulation-based clinical pathways, teaching residents how to interpret model cards, regulatory documentation. Clinical examples such as stroke triage, Urinary tract calculi detection, AI-CAD in mammography, false-positive detection are used to anchor theory in practice. The article also addresses critical domains of AI governance: model transparency, ethical dilemmas, algorithmic bias, the role of residents in human-in-the-loop oversight systems. It outlines mentorship, faculty development strategies to build institutional readiness, proposes a roadmap to future-proof radiology education. This includes exposure to foundation models, vision-language systems, multi-agent workflows, global best practices in post-deployment AI monitoring. This pragmatic framework aims to serve as a guide for residency programs adapting to the next era of radiology practice.

Diagnostic and Technological Advances in Magnetic Resonance (Focusing on Imaging Technique and the Gadolinium-Based Contrast Media), Computed Tomography (Focusing on Photon Counting CT), and Ultrasound-State of the Art.

Runge VM, Heverhagen JT

pubmed logopapersJun 9 2025
Magnetic resonance continues to evolve and advance as a critical imaging modality for disease diagnosis and monitoring. Hardware and software advances continue to propel this modality to the forefront of the field of diagnostic imaging. Next generation MR contrast media, specifically gadolinium chelates with improved relaxivity and stability (relative to the provided contrast effect), have emerged providing a further boost to the field. Concern regarding gadolinium deposition in the body with primarily the weaker gadolinium chelates (which have been now removed from the market, at least in Europe) continues to be at the forefront of clinicians' minds. This has driven renewed interest in possible development of manganese-based contrast media. The development of photon counting CT and its clinical introduction have made possible a further major advance in CT image quality, along with the potential for decreasing radiation dose. The possibility of major clinical advances in thoracic, cardiac, and musculoskeletal imaging were first recognized, with its broader impact - across all organ systems - now also recognized. The utility of routine acquisition (without penalty in time or radiation dose) of full spectral multi-energy data is now also being recognized as an additional major advance made possible by photon counting CT. Artificial intelligence is now being used in the background across most imaging platforms and modalities, making possible further advances in imaging technique and image quality, although this field is nowhere yet near to realizing its full potential. And last, but not least, the field of ultrasound is on the cusp of further major advances in availability (with development of very low-cost systems) and a possible new generation of microbubble contrast media.

Automated Vessel Occlusion Software in Acute Ischemic Stroke: Pearls and Pitfalls.

Aziz YN, Sriwastwa A, Nael K, Harker P, Mistry EA, Khatri P, Chatterjee AR, Heit JJ, Jadhav A, Yedavalli V, Vagal AS

pubmed logopapersJun 9 2025
Software programs leveraging artificial intelligence to detect vessel occlusions are now widely available to aid in stroke triage. Given their proprietary use, there is a surprising lack of information regarding how the software works, who is using the software, and their performance in an unbiased real-world setting. In this educational review of automated vessel occlusion software, we discuss emerging evidence of their utility, underlying algorithms, real-world diagnostic performance, and limitations. The intended audience includes specialists in stroke care in neurology, emergency medicine, radiology, and neurosurgery. Practical tips for onboarding and utilization of this technology are provided based on the multidisciplinary experience of the authorship team.

Current utilization and impact of AI LVO detection tools in acute stroke triage: a multicenter survey analysis.

Darkhabani Z, Ezzeldin R, Delora A, Kass-Hout O, Alderazi Y, Nguyen TN, El-Ghanem M, Anwoju T, Ali Z, Ezzeldin M

pubmed logopapersJun 7 2025
Artificial intelligence (AI) tools for large vessel occlusion (LVO) detection are increasingly used in acute stroke triage to expedite diagnosis and intervention. However, variability in access and workflow integration limits their potential impact. This study assessed current usage patterns, access disparities, and integration levels across U.S. stroke programs. Cross-sectional, web-based survey of 97 multidisciplinary stroke care providers from diverse institutions. Descriptive statistics summarized demographics, AI tool usage, access, and integration. Two-proportion Z-tests assessed differences across institutional types. Most respondents (97.9%) reported AI tool use, primarily Viz AI and Rapid AI, but only 62.1% consistently used them for triage prior to radiologist interpretation. Just 37.5% reported formal protocol integration, and 43.6% had designated personnel for AI alert response. Access varied significantly across departments, and in only 61.7% of programs did all relevant team members have access. Formal implementation of the AI detection tools did not differ based on the certification (z = -0.2; <i>p</i> = 0.4) or whether the program was academic or community-based (z =-0.3; <i>p</i> = 0.3). AI-enabled LVO detection tools have the potential to improve stroke care and patient outcomes by expediting workflows and reducing treatment delays. This survey effectively evaluated current utilization of these tools and revealed widespread adoption alongside significant variability in access, integration, and workflow standardization. Larger, more diverse samples are needed to validate these findings across different hospital types, and further prospective research is essential to determine how formal integration of AI tools can enhance stroke care delivery, reduce disparities, and improve clinical outcomes.

A Decade of Advancements in Musculoskeletal Imaging.

Wojack P, Fritz J, Khodarahmi I

pubmed logopapersJun 6 2025
The past decade has witnessed remarkable advancements in musculoskeletal radiology, driven by increasing demand for medical imaging and rapid technological innovations. Contrary to early concerns about artificial intelligence (AI) replacing radiologists, AI has instead enhanced imaging capabilities, aiding in automated abnormality detection and workflow efficiency. MRI has benefited from acceleration techniques that significantly reduce scan times while maintaining high-quality imaging. In addition, novel MRI methodologies now support precise anatomic and quantitative imaging across a broad spectrum of field strengths. In CT, dual-energy and photon-counting technologies have expanded diagnostic possibilities for musculoskeletal applications. This review explores these key developments, examining their impact on clinical practice and the future trajectory of musculoskeletal radiology.

Magnetic resonance imaging and the evaluation of vestibular schwannomas: a systematic review

Lee, K. S., Wijetilake, N., Connor, S., Vercauteren, T., Shapey, J.

medrxiv logopreprintJun 6 2025
IntroductionThe assessment of vestibular schwannoma (VS) requires a standardized measurement approach as growth is a key element in defining treatment strategy for VS. Volumetric measurements offer higher sensitivity and precision, but existing methods of segmentation, are labour-intensive, lack standardisation and are prone to variability and subjectivity. A new core set of measurement indicators reported consistently, will support clinical decision-making and facilitate evidence synthesis. This systematic review aimed to identify indicators used in 1) magnetic resonance imaging (MRI) acquisition and 2) measurement or 3) growth of VS. This work is expected to inform a Delphi consensus. MethodsSystematic searches of Medline, Embase and Cochrane Central were undertaken on 4th October 2024. Studies that assessed the evaluation of VS with MRI, between 2014 and 2024 were included. ResultsThe final dataset consisted of 102 studies and 19001 patients. Eighty-six (84.3%) studies employed post contrast T1 as the MRI acquisition of choice for evaluating VS. Nine (8.8%) studies additionally employed heavily weighted T2 sequences such as constructive interference in steady state (CISS) and FIESTA-C. Only 45 (44.1%) studies reported the slice thickness with the majority 38 (84.4%) choosing <3mm in thickness. Fifty-eight (56.8%) studies measured volume whilst 49 (48.0%) measured the largest linear dimension; 14 (13.7%) studies used both measurements. Four studies employed semi-automated or automated segmentation processes to measure the volumes of VS. Of 68 studies investigating growth, 54 (79.4%) provided a threshold. Significant variation in volumetric growth was observed but the threshold for significant percentage change reported by most studies was 20% (n = 18). ConclusionSubstantial variation in MRI acquisition, and methods for evaluating measurement and growth of VS, exists across the literature. This lack of standardization is likely attributed to resource constraints and the fact that currently available volumetric segmentation methods are very labour-intensive. Following the identification of the indicators employed in the literature, this study aims to develop a Delphi consensus for the standardized measurement of VS and uptake in employing a data-driven artificial intelligence-based measuring tools.

Deep Learning Approaches for Brain Tumor Detection and Classification Using MRI Images (2020 to 2024): A Systematic Review.

Bouhafra S, El Bahi H

pubmed logopapersJun 1 2025
Brain tumor is a type of disease caused by uncontrolled cell proliferation in the brain leading to serious health issues such as memory loss and motor impairment. Therefore, early diagnosis of brain tumors plays a crucial role to extend the survival of patients. However, given the busy nature of the work of radiologists and aiming to reduce the likelihood of false diagnoses, advancing technologies including computer-aided diagnosis and artificial intelligence have shown an important role in assisting radiologists. In recent years, a number of deep learning-based methods have been applied for brain tumor detection and classification using MRI images and achieved promising results. The main objective of this paper is to present a detailed review of the previous researches in this field. In addition, This work summarizes the existing limitations and significant highlights. The study systematically reviews 60 articles researches published between 2020 and January 2024, extensively covering methods such as transfer learning, autoencoders, transformers, and attention mechanisms. The key findings formulated in this paper provide an analytic comparison and future directions. The review aims to provide a comprehensive understanding of automatic techniques that may be useful for professionals and academic communities working on brain tumor classification and detection.
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