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Enabling AI-Based Prediction of Neoadjuvant Treatment Response: A FAIR Multimodal Dataset Within EUCAIM.

June 29, 2026pubmed logopapers

Authors

González López M,Álvarez Pérez RM,Rey Garduño F,Jiménez-Hoyuela García JM,Castell Monsalve FJ,Parra Calderón CL

Affiliations (3)

  • Computational Health Informatics Group. IBiS/HUVR/CSIC/US.
  • Molecular Imaging, Theragnosis and Precision Nuclear Medicine Group. IBiS/Department of Nuclear Medicine. HUVR/CSIC/US.
  • Department of Radiology. HUVR.

Abstract

This work presents a FAIR-compliant, multimodal PET-CT and clinical dataset developed within the EUCAIM framework to support future AI-based prediction of response to NST in LABC patients. A real-world dataset was curated, harmonized, and integrated into the EUCAIM CDM within a federated infrastructure. While predictive modeling is ongoing, this study focuses on data preparation and infrastructure, key bottlenecks for AI development, demonstrating the feasibility of integrating local hospital data into a European federated ecosystem to enable future multicentric AI applications.

Topics

Neoadjuvant TherapyPositron Emission Tomography Computed TomographyBreast NeoplasmsArtificial IntelligenceJournal Article

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