Validation study comparing Artificial intelligence for fully automatic aortic aneurysms Segmentation and diameter Measurements On contrast and non-contrast enhanced computed Tomography (ASMOT).

Authors

Gatinot A,Caradu C,Stephan L,Foret T,Rinckenbach S

Affiliations (5)

  • Department of Vascular and Endovascular Surgery, Besançon University Hospital, Besançon, France. Electronic address: [email protected].
  • Department of Vascular Surgery, Bordeaux University Hospital, Bordeaux, France. Electronic address: [email protected].
  • Nurea, F-33000, Bordeaux, France. Electronic address: [email protected].
  • Department of Vascular and Endovascular Surgery, Besançon University Hospital, Besançon, France; Université de Franche-Comté, SINERGIES, F-25000 Besançon, France. Electronic address: [email protected].
  • Department of Vascular and Endovascular Surgery, Besançon University Hospital, Besançon, France; Université de Franche-Comté, SINERGIES, F-25000 Besançon, France. Electronic address: [email protected].

Abstract

Accurate aortic diameter measurements are essential for diagnosis, surveillance, and procedural planning in aortic disease. Semi-automatic methods remain widely used but require manual corrections, which can be time-consuming and operator-dependent. Artificial intelligence (AI)-driven fully automatic methods may offer improved efficiency and measurement accuracy. This study aims to validate a fully automatic method against a semi-automatic approach using computed tomography angiography (CTA) and non-contrast CT scans. A monocentric retrospective comparative study was conducted on patients who underwent endovascular aortic repair (EVAR) for infrarenal, juxta-renal or thoracic aneurysms and a control group. Maximum aortic wall-to-wall diameters were measured before and after repair using a fully automatic software (PRAEVAorta2®, Nurea, Bordeaux, France) and compared to measurements performed by two vascular surgeons using a semi-automatic approach on CTA and non-contrast CT scans. Correlation coefficients (Pearson's R) and absolute differences were calculated to assess agreement. A total of 120 CT scans (60 CTA and 60 non-contrast CT) were included, comprising 23 EVAR, 4 thoracic EVAR, 1 fenestrated EVAR, and 4 control cases. Strong correlations were observed between the fully automatic and semi-automatic measurements in both CTA and non-contrast CT. For CTA, correlation coefficients ranged from 0.94 to 0.96 (R<sup>2</sup> = 0.88-0.92), while for non-contrast CT, they ranged from 0.87 to 0.89 (R<sup>2</sup> = 0.76-0.79). Median absolute differences in aortic diameter measurements varied between 1.1 mm and 4.2 mm across the different anatomical locations. The fully automatic method demonstrated a significantly faster processing time, with a median execution time of 73 seconds (IQR: 57-91) compared to 700 (IQR: 613-800) for the semi-automatic method (p < 0.001). The fully automatic method demonstrated strong agreement with semi-automatic measurements for both CTA and non-contrast CT, before and after endovascular repair in different aortic locations, with significantly reduced analysis time. This method could improve workflow efficiency in clinical practice and research applications.

Topics

Journal Article
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