Deep Learning-Based Identification of Surgical Candidacy for Cervical Spinal Cord Decompression.
Authors
Affiliations (3)
Affiliations (3)
- Department of Neurosurgery, University of California, Los Angeles, CA, USA.
- Department of Radiological Sciences, University of California, Los Angeles, CA, USA.
- Department of Neurosurgery, University of California, Los Angeles, CA, USA [email protected].
Abstract
Artificial intelligence has previously demonstrated the capability to interpret cervical spine imaging. The present study aims to identify whether deep learning can be harnessed to triage patients into operative and nonoperative groups based on imaging findings, an intricate process complicated by the high rates of background findings. A deep-learning algorithm was trained to segment the spinal canal and spinal cord on 100 axial cervical spine magnetic resonance images to generate a biomarker for cervical stenosis, defined as the minimum difference in cross-sectional area between these structures. After training, the model and its biomarker were tested against a cohort of 147 consecutive patients evaluated in the outpatient setting by a group of board-certified neurosurgeons at our institution for complaints related to their cervical spines. The mean minimum difference in cross-sectional area between the spinal canal and spinal cord for our cohort was 35.90 ± 25.00 mm<sup>2</sup> for patients who ultimately underwent surgical decompression and 48.55 ± 33.52 mm<sup>2</sup> for patients who did not (<i>P</i> = 0.005). Using this biomarker, the model distinguished between surgical and nonsurgical patients with relatively high accuracy (area under the curve 0.79). The present work describes a proof-of-concept model for triaging patients with cervical stenosis into surgical and nonsurgical cohorts based on imaging findings. In doing this, we aim to provide an additional supportive metric for referring providers to consult when considering whether to refer patients to spine surgery. Neck pain is a common presenting symptom in the primary care setting, yet determining which patients could benefit from a surgical consultation is often a nuanced task. Deep learning has the potential to assist with the radiographic component of the referral process by identifying markers suggestive of operative candidacy, providing an objective metric for referring providers to consider when deciding whether surgical consultation is warranted. This may help triage patients by expediting referral of operative patients to spine surgeons and redirecting nonoperative patients to physiatry, physical therapy, or other conservative management.