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BONBID-HIE 2023: Lesion Segmentation Challenge in BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy.

December 11, 2025pubmed logopapers

Authors

Bao R,Foster AN,Song Y,Vyas R,Kesri A,Toubal IE,Kazemi ES,Rahmon G,Kucukpinar T,Almansour M,Ho ML,Palaniappan K,Ninalga D,Koirala CP,Mohapatra S,Schlaug G,Wodzinski M,Muller H,Ellis DG,Aizenberg MR,Arda Aydin M,Abdinli E,Unal G,Tahmasebi N,Punithakumar K,Song T,Peng Y,Bates SV,Hirschtick R,Ellen Grant P,Ou Y

Abstract

Hypoxic Ischemic Encephalopathy (HIE) represents a brain dysfunction, affecting approximately 1 to 5 per 1000 full-term neonates. The precise delineation and segmentation of HIE-related lesions in neonatal brain Magnetic Resonance Images (MRI) are pivotal in advancing outcome predictions, identifying patients at high risk, elucidating neurological manifestations, and assessing treatment efficacies. Despite its importance, the development of algorithms for segmenting HIE lesions from MRI volumes has been impeded by data scarcity. Addressing this critical gap, we organized the first BONBID-HIE challenge with diffusion MRI data (Apparent Diffusion Coefficient (ADC) maps) for HIE lesion segmentation, in conjunction with the MICCAI 2023. Totally 14 algorithms were submitted, employing a gamut of cutting-edge automatic machine-learning-based segmentation algorithms. Our comprehensive analysis of HIE lesion segmentation and submitted algorithms facilitates an in-depth evaluation of the current technological zenith, outlines directions for future advancements, and highlights persistent hurdles. To foster ongoing research and benchmarking, the annotated HIE dataset, developed algorithm dockers, and unified evaluation codes are accessible through a dedicated online platform (https://bonbid-hie2023.grand-challenge.org).

Topics

Journal Article

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