A Multi-Task Deep Learning Model for Pediatric Echocardiography Analysis
Authors
Affiliations (1)
Affiliations (1)
- Stanford University
Abstract
BackgroundCongenital heart defects afflict nearly 1% of all births worldwide. While deep learning algorithms have shown significant promise in automating and improving adult echocardiography analysis, similar progress has not been observed in pediatric echocardiography. Specifically, existing pediatric-based models are limited to single tasks and specific echocardiographic views. To address this, we introduce EchoAI-Peds, the first multi-task deep learning model for pediatric echocardiography. Our model was developed using the most comprehensive set of pediatric labels to date and is designed to integrate information from multiple echocardiographic views simultaneously. MethodsA video-based vision transformer was trained to simultaneously detect 28 congenital heart defects, structural and functional abnormalities, repairs, and interventions directly from complete pediatric echocardiography studies with multiple videos. During inference, our model integrates information from all available views to produce unified study-level predictions. Our model was developed using over 700,000 videos derived from more than 11,000 studies at Stanford Medicine. Model efficacy was tested on an internal held-out dataset. In addition, model generalizability was tested on a spatially and temporally distinct patient cohort at the Childrens Hospital of Philadelphia. ResultsOur model achieved macro-averaged AUROC values of 0.91 (95% CI: 0.90-0.92) and 0.89 (95% CI: 0.88-0.90) on the internal and external test sets, respectively. Moreover, our model significantly outperformed adult-based echocardiography foundation models trained on substantially larger datasets (p < 0.001). Finally, our model demonstrated robust performance across patient age, patient sex, and studies with varying number of videos. ConclusionsOur findings demonstrate the remarkable potential for multi-task deep learning models to aid the interpretation of pediatric echocardiograms. In addition, our results underscore the need for models that are specifically tailored to pediatric populations.