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Multimodality imaging approaches for diagnosis of cardiac amyloidosis.

November 4, 2025pubmed logopapers

Authors

Rojulpote C,Cuddy SAM,Kijewski MF,Dorbala S

Affiliations (3)

  • Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America; Department of Radiology, Cardiovascular Imaging Section, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.
  • Department of Radiology, Cardiovascular Imaging Section, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.
  • Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America; Department of Radiology, Cardiovascular Imaging Section, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America. Electronic address: [email protected].

Abstract

Cardiac amyloidosis is increasingly recognized as an underdiagnosed cause of heart failure. This review article provides an overview of the role of multimodality cardiovascular imaging in raising the suspicion of cardiac amyloidosis, confirming the diagnosis, providing risk assessment and detection of myocardial changes in response to therapy. The clinical use of multimodality imaging in diagnosing cardiac amyloidosis is illustrated through a case-based approach. Finally, the emerging role of cardiac positron emission tomography as well as artificial intelligence in cardiac amyloidosis is discussed.

Topics

Journal Article

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