Back to all papers

[Artificial intelligence algorithm for bone age estimation].

May 6, 2026pubmed logopapers

Authors

Peralta-Cortázar C,Santiago-Loya Z,Rivera-Villanueva TM,Pérez-Godínez DO,Padilla-Solís OAJ,Urzúa-González AR,González AP,Paque-Bautista C,Luna-Anguiano JLF,Sosa-Bustamante GP

Affiliations (4)

  • Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No. 48, División de Pediatría. León, Guanajuato, México.
  • Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatria No 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.
  • Grupo Multidisciplinario de Investigación en Inteligencia Artificial en Salud. León, Guanajuato, México.
  • Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatria No 48, Dirección General. León, Guanajuato, México.

Abstract

Bone age (BA) estimation with automated methods can eliminate interindividual variation. To evaluate BA by creating an artificial intelligence (AI) algorithm in a pediatric population from the Bajío region of Mexico. Observational, cross-sectional, retrospective, analytical study. Left-hand radiographs of children under 18 years of age, obtained from the Radiology Department database were included to create the AI algorithm for estimating BA. The BA result obtained by AI was compared with that obtained by 2 expert observers using the Greulich and Pyle method. 271 radiographs were analyzed to assess BA and this was similar between observers 1, 2, and AI when considering all images (p = 0.68). The time taken to estimate BA was longer with AI (p < 0.001). AI measurement showed no differences between chronological age (CA) and BA when considering both the total number of images (p = 0.12) and when they were distributed by age group: < 6 years, 6 to < 10 years, and ≥ 10 years (p = 0.60, p = 0.06, p = 0.67, respectively). The highest EO concordance correlation coefficients (CCCs) were recorded when all images were evaluated (observer 1 and 2, observer 1 and AI, and observer 2 and AI [p < 0.001, in all 3 scenarios]). The AI algorithm allows for objective estimation of BA in children and adolescents as a first training approach; its refinement will optimize its use and utility in clinical practice.

Topics

Age Determination by SkeletonAlgorithmsArtificial IntelligenceEnglish AbstractJournal ArticleObservational Study

Ready to Sharpen Your Edge?

Subscribe to join 11k+ peers who rely on RadAI Slice. Get the essential weekly briefing that empowers you to navigate the future of radiology.

We respect your privacy. Unsubscribe at any time.