Back to all papers

Human-AI Interaction in Interventional Radiology: A Narrative Review of Current Applications, Challenges, and Future Directions.

June 22, 2026pubmed logopapers

Authors

Mariotti F,Cacioppa LM,Rossini N,Bruno A,Francavilla G,Felicioli A,Macchini M,Coppola A,Cellina M,Floridi C

Affiliations (6)

  • Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, 60126 Ancona, Italy.
  • Division of Interventional Radiology, Department of Radiological Sciences, University Hospital "Azienda Ospedaliero Universitaria delle Marche", 60126 Ancona, Italy.
  • Division of Radiology, Department of Radiological Sciences, University Hospital "Azienda Ospedaliero Universitaria delle Marche", 60126 Ancona, Italy.
  • Diagnostic and Interventional Radiology Unit, Circolo Hospital, ASST Sette Laghi, 21100 Varese, Italy.
  • Department of Medicine and Technological Innovation, Insubria University, 21100 Varese, Italy.
  • Radiology Department, ASST Fatebenefratelli Sacco, 20121 Milan, Italy.

Abstract

Traditional evaluations of artificial intelligence (AI) systems in the dynamic, operator-dependent, and time-sensitive field of interventional radiology (IR), focusing solely on algorithmic performance, often fail to capture their real-world clinical impact. This narrative review aims to provide an overview of the current state of the art of AI integration in IR through human-AI interaction (HAI), while offering a critical perspective on their clinical integration, limitations, and future directions. A comprehensive survey of recent literature was performed, focusing on AI applications across procedural phases. The review emphasizes systems providing decision support, real-time procedural verification, and immersive interfaces (augmented and virtual reality), while critically evaluating determinants of effective clinical adoption. AI has shown preliminary potential to support operator performance in selected interventional radiology tasks, although most applications remain experimental, retrospective, or evaluated in phantom or preclinical settings. Potential benefits include structuring uncertainty in patient selection and procedural planning, supporting assessment of device positioning and treatment outcomes, and integrating AI-derived outputs into the operator's spatial field through immersive technologies. The clinical utility of these systems appears to be influenced by human-AI interaction, with interpretability, workflow integration, and trust calibration representing key determinants of effective use beyond algorithmic accuracy alone. The potential value of AI in interventional radiology appears to derive from its integration into human decision-making rather than from standalone predictive performance alone. A human-centered, interaction-based model supports understanding current applications, address challenges, and guide the development of adaptive, real-time systems for dynamic procedural environments.

Topics

Journal ArticleReview

Ready to Sharpen Your Edge?

Subscribe to join 11k+ peers who rely on RadAI Slice. Get the essential weekly briefing that empowers you to navigate the future of radiology.

We respect your privacy. Unsubscribe at any time.