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Deep learning based volumetric analysis of infrarenal abdominal aortic aneurysms characterized on CTA.

January 10, 2026pubmed logopapers

Authors

Weiss D,Hager T,Lin M,Sritharan D,Bousabarah K,Renninghoff D,Holler W,Simmons K,Haubold J,Loh S,Fischer U,Chapiro J,Deuschl C,Aboian M,Aboian E,Aneja S

Affiliations (11)

  • Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
  • Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
  • Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.
  • Visage Imaging, Inc., San Diego, CA, USA.
  • Visage Imaging, GmbH, Berlin, Germany.
  • Department of Vascular Surgery and Endovascular Therapy, Yale School of Medicine, New Haven, CT, USA.
  • Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
  • Department of Vascular Surgery and Endovascular Therapy, Yale School of Medicine, New Haven, CT, USA. [email protected].
  • Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA. [email protected].
  • Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA. [email protected].

Abstract

Volumetric assessment of abdominal aortic aneurysms (AAA) offers precise pre- and post-endovascular aortic repair (EVAR) evaluation but is laborious. The primary aim was to train and validate a network facilitating automated segmentation and volume determination of pre- and post-EVAR infrarenal AAAs displayed on computed tomography angiographies (CTA). Secondary aim was evaluation of workflow acceleration. Model was trained on ground truth segmentations. Internal and external validation was performed. AI-generated volumes of total aneurysm, lumen, and thrombus were correlated with ground truth. Model-enabled efficiency gains and semi-automatic AAA segmentations performed by three surgeons were measured. For total aneurysm, mean Dice similarity coefficient was 0.972 ± 0.013 and 0.960 ± 0.035 in internal and external validation. AI-generated thrombus volumes showed a very strong correlation with ground truth in internal (r = 0.996) and external validation (r = 0.940). Mean algorithm-facilitated time savings of 117.1 seconds (56.0%) were demonstrated for total aneurysm. Our institution-agnostic network enables automated volumetric analysis of AAAs.

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Journal Article

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