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Multi-modal personalized federated learning with adaptive differential privacy for medical image classification and a privacy-preserving approach.

May 12, 2026pubmed logopapers

Authors

M AS,Chowdhary CL

Affiliations (2)

  • School of Computer Science Engineering and Information Systems, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India.
  • School of Computer Science Engineering and Information Systems, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India. [email protected].

Abstract

Deep learning on medical images classification intervention needs to use large data on multi-institutional datasets but privacy laws inhibit sharing of data (GDPR, HIPAA). Federated Learning (FL) facilitates collaborative training without data transfer; until now, the known methods can only address privacy, personalisation, and accuracy not at the same time in a multi-modal environment. We present MM-PFL-ADP, a framework that combines Vision Transformer (ViT) based multi-modal feature extraction in four new elements: (i) privacy budget allocation (independent of number of samples): Fisher information-based adaptive per-parameter privacy budget allocation ([Formula: see text]); (ii) personalisation masks: dynamic KL divergence based personalisation masks; (iii) respect The framework gives formal client-level [Formula: see text]-DP guarantees on transmitted gradient updates, in [Formula: see text] simulated medical institutions. On the MRI-MS dataset, MM-PFL-ADP achieves [Formula: see text] accuracy (95% CI: 96.9-[Formula: see text]) at [Formula: see text], outperforming FedAvg ([Formula: see text]) and DP-FedAvg ([Formula: see text]) by large margins ([Formula: see text]). The framework is [Formula: see text] faster than FedAvg (47 vs. 85 rounds), has [Formula: see text] less total communication and keeps [Formula: see text] accuracy in case of extreme heterogeneity in data ([Formula: see text]). The probability of membership inference attack has decreased to 52.1 which was close to the random baseline ([Formula: see text]). MM-PFL-ADP shows that the concepts of privacy, personalisation, and accuracy are synergistic, but not oppositional to federated medical AI. The single-system Fisher information framework greatly simplifies the hyperparameter tuning problem and can meet formal privacy criteria. Before being deployed, prospective validation against the performance of expert radiologists is desired.

Topics

Journal Article

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