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ContiMorph: An unsupervised learning framework for cardiac motion tracking with time-continuous diffeomorphism.

June 24, 2026pubmed logopapers

Authors

Jiang M,Ruan X,Zheng L,Zhang X,Zheng Y,Yu C,Ruan D,Liu H

Affiliations (7)

  • School of Computer Science and Technology, Zhejiang Sci-Tech University, Hangzhou 310018, China.
  • School of Information and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, China.
  • Department of Nephrology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
  • School of Computer Science, Civil Aviation Flight University of China, Guanghan 618307, China.
  • School of Big Data and Statistics, Anhui University, Hefei 230601, China.
  • School of Computer Science and Technology, Zhejiang Sci-Tech University, Hangzhou 310018, China. Electronic address: [email protected].
  • College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, China.

Abstract

Cardiac motion tracking is essential for evaluating cardiac function and diagnosing cardiovascular diseases. However, existing tracking methods primarily depend on scaling-and-squaring (SS) integration to derive discrete Lagrangian motion fields. This dependency limits the ability to fully exploit the temporal continuity of cardiac motion, leading to suboptimal tracking accuracy. In this paper, we introduce ContiMorph, a novel unsupervised learning framework for time-continuous motion tracking in cardiac image sequences. Specifically, ContiMorph integrates a frame-aware U-Net with time-embedded transformer module to learn temporally continuous intra-frame motion fields, which are then composed into time-continuous Lagrangian motion fields for precise tracking. Moreover, we propose a time-continuous Lagrangian motion constraint to ensure diffeomorphic topology throughout the image sequence. Combined with semigroup regularization during training, this constraint effectively leverages temporal information and eliminates the need for SS integration. Extensive experiments on cardiac magnetic resonance imaging (MRI) and echocardiography (US) datasets demonstrate that ContiMorph outperforms existing motion-tracking methods, achieving state-of-the-art performance across diverse imaging modalities. The code is publicly available at https://github.com/luffhhh/ContiMorph.

Topics

Journal Article

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