Emerging trends in NanoTheranostics: Integrating imaging and therapy for precision health care.
Authors
Affiliations (6)
Affiliations (6)
- Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: [email protected].
- Chemistry/Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
- Biomedical Science, Drug Design, Zewail City of Science and Technology, Giza, Egypt.
- Microbiology Department, Faculty of Science, Cairo University, Giza, Egypt.
- Biotechnology Department, Faculty of Agriculture, Cairo University, Giza, Egypt.
- Chemistry / Biochemistry Program, Faculty of Science, Cairo University, Giza, Egypt.
Abstract
Nanotheranostics has garnered significant interest for its capacity to improve customized healthcare via targeted and efficient treatment alternatives. Nanotheranostics promises an innovative approach to precision medicine by integrating therapeutic and diagnostic capabilities into nanoscale devices. Nanotheranostics provides an integrated approach that improves diagnosis and facilitates real-time, tailored treatment, revolutionizing patient care. Through the application of nanotheranostic devices, outcomes can be modified for patients on an individualized therapeutic level by taking into consideration individual differences in disease manifestation as well as treatment response. In this review, no aspect of imaging in nanotheranostics is excluded, thus including MRI and CT as well as PET and OI, which are essential for comprehensive analysis needed in medical decision making. Integration of AI and ML into theranostics facilitates predicting treatment outcomes and personalizing the approaches to the methods, which significantly enhances reproducibility in medicine. In addition, several nanoparticles such as lipid-based and polymeric particles, iron oxide, quantum dots, and mesoporous silica have shown promise in diagnosis and targeted drug delivery. These nanoparticles are capable of treating multiple diseases such as cancers, some other neurological disorders, and infectious diseases. While having potential, the field of nanotheranostics still encounters issues regarding clinical applicability, alongside some regulatory hurdles pertaining to new therapeutic agents. Advanced research in this sphere is bound to enhance existing perspectives and fundamentally aid the integration of nanomedicine into conventional health procedures, especially relating to efficacy and the growing emphasis on safe, personalized healthcare.