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AURA-CVC: Autonomous Ultrasound-guided Robotic Assistance for Central Venous Catheterization.

February 25, 2026pubmed logopapers

Authors

Raina D,Al-Zogbi L,Teixeira B,Singh V,Kapoor A,Fleiter T,Bell MAL,Pandian V,Krieger A

Affiliations (9)

  • Malone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Indian Institute of Technology Mandi, Himachal Pradesh, 175005, India.
  • Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Vanderbilt University, Nashville, TN, 37235, USA.
  • Medical Imaging Technologies, Siemens Medical Solutions, Inc., Princeton, NJ 08540, USA.
  • R. Cowley Shock Trauma Center, Department of Diagnostic Radiology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
  • Johns Hopkins University, Baltimore, MD, USA.
  • Ross and Carol Nese College of Nursing, The Pennsylvania State University, University Park, PA 16802, USA.
  • Whiting School of Engineering and Malone Centre for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD 21218, USA. [email protected].

Abstract

Central venous catheterization (CVC) is a critical medical procedure for vascular access, hemodynamic monitoring, and life-saving interventions. Its success remains challenging due to the need for continuous ultrasound-guided visualization of a target vessel and approaching needle, which is further complicated by anatomical variability and operator dependency. Errors in needle placement can lead to life-threatening complications. While robotic systems offer a potential solution, achieving full autonomy remains challenging. In this work, we propose an end-to-end robotic ultrasound-guided CVC pipeline, from scan initialization to needle insertion. We introduce a deep-learning model to identify clinically relevant anatomical landmarks from a depth image of the patient's neck, obtained using an RGB-D camera, to autonomously define the scanning region and paths. Then, a robot motion planning framework is proposed to scan, segment, reconstruct, and localize vessels (veins and arteries), followed by the identification of the optimal insertion zone. Finally, a needle guidance module plans the insertion under ultrasound guidance with operator's feedback. This pipeline was validated on a high-fidelity commercial phantom across 10 simulated clinical scenarios. The proposed pipeline achieved 10 out of 10 successful needle placements on the first attempt. Vessels were reconstructed with a mean error of 2.15 mm, and autonomous needle insertion was performed with an error less than or close to 1 mm. To our knowledge, this is the first robotic CVC system demonstrated on a high-fidelity phantom with integrated planning, scanning, and insertion. Experimental results show its potential for clinical translation.

Topics

Journal Article

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