Arthroscopy-validated diagnostic performance of sub-5-min deep learning super-resolution 3T knee MRI in children and adolescents.
Authors
Affiliations (8)
Affiliations (8)
- Department of Radiology, Grossman School of Medicine, New York University, 660 1 Ave, 3 Floor, Rm 313, New York, NY, 10016, USA.
- Department of Radiology, University Hospital Basel, Basel, Switzerland.
- Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
- Department of Radiology, University Hospital Tübingen, Tübingen, Germany.
- Medscanlagos Radiology, Cabo Frio, Brazil.
- Department of Radiology, Hospital Do Coraçao, São Paulo, Brazil.
- Centre for Data Analytics, Bond University, Gold Coast, Australia.
- Department of Radiology, Grossman School of Medicine, New York University, 660 1 Ave, 3 Floor, Rm 313, New York, NY, 10016, USA. [email protected].
Abstract
This study aims to determine the diagnostic performance of sub-5-min combined sixfold parallel imaging (PIx3)-simultaneous multislice (SMSx2)-accelerated deep learning (DL) super-resolution 3T knee MRI in children and adolescents. Children with painful knee conditions who underwent PIx3-SMSx2-accelerated DL super-resolution 3T knee MRI and arthroscopy between October 2022 and December 2023 were retrospectively included. Nine fellowship-trained musculoskeletal radiologists independently scored the MRI studies for image quality and the presence of artifacts (Likert scales, range: 1 = very bad/severe, 5 = very good/absent), as well as structural abnormalities. Interreader agreements and diagnostic performance testing was performed. Forty-four children (mean age: 15 ± 2 years; range: 9-17 years; 24 boys) who underwent knee MRI and arthroscopic surgery within 22 days (range, 2-133) were evaluated. Overall image quality was very good (median rating: 5 [IQR: 4-5]). Motion artifacts (5 [5-5]) and image noise (5 [4-5]) were absent. Arthroscopy-verified abnormalities were detected with good or better interreader agreement (κ ≥ 0.74). Sensitivity, specificity, accuracy, and AUC values were 100%, 84%, 93%, and 0.92, respectively, for anterior cruciate ligament tears; 71%, 97%, 93%, and 0.84 for medial meniscus tears; 65%, 100%, 86%, and 0.82 for lateral meniscus tears; 100%, 100%, 100%, and 1.00 for discoid lateral menisci; 100%, 95%, 96%, and 0.98 for medial patellofemoral ligament tears; and 55%, 100%, 98%, and 0.77 for articular cartilage defects. Clinical sub-5-min PIx3-SMSx2-accelerated DL super-resolution 3T knee MRI provides excellent image quality and high diagnostic performance for diagnosing internal derangement in children and adolescents.