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Deep Learning-Based Segmentation of Fetal Anatomical Structures in the First Trimester.

May 6, 2026pubmed logopapers

Authors

Hong S,Kim O,Kang BS,Won S,Ko HS,Byun JH,Wie JH,Kwon JY,Lee KE,Shin JE,Kim YH,Lee J,Choi KY,Park IY

Affiliations (6)

  • Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Department of Obstetrics and Gynecology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Department of Obstetrics and Gynecology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Department of Obstetrics and Gynecology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Department of Obstetrics and Gynecology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • AI Vision Group, Samsung Medison Co. Ltd, Seoul, Republic of Korea.

Abstract

To develop and evaluate an artificial intelligence (AI) system that automatically identifies and classifies the fetal structures in the first trimester. Over 20,000 ultrasound images from first-trimester fetuses were prospectively collected from four university hospitals in the Republic of Korea. Images were annotated according to segmentation-specific structures by anatomical regions, including the head, neck, thorax, abdomen, extremities, and spine, based on standardized guidelines. The YOLACT model, which enabels real-time instance segmentation, was used to detect and segment fetal structures. The dataset was randomly divided into a training set (95%) and a test set (5%). Model performance was evaluated using detection accuracy, mean average precision (mAP), and frames per second (FPS). The YOLACT model achieved an overall anatomical detection accuracy of 98.4%. High segmentation performance (F1-score > 0.950) was observed for well-defined structures such as the cranium, heart, and abdominal circumference. Structures like the nasal bone and extremities had relatively lower recall. The model's mAP at IoU 0.5 was 0.622, and real-time processing was confirmed with a speed of 25.4 FPS. The YOLACT-based AI model demonstrated accurate and efficient segmentation of fetal structures in the first trimester, supporting its potential for real-time clinical application in early anomaly screening.

Topics

Journal Article

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