Mice with ischemic stroke receiving human neural stem cell transplants showed robust brain recovery, measured using AI-based limb tracking.
Key Details
- 1Researchers from USC, University of Zurich, and ETH Zurich transplanted reprogrammed human blood cells (neural stem cells) into post-stroke mice brains.
- 2Stem cell transplants performed one week after stroke enhanced neuron and blood vessel growth, reduced inflammation, and improved neuronal connectivity.
- 3AI-powered movement analysis tracked significant functional improvements in motor skills and gait among treated mice.
- 4Majority of transplanted cells became GABAergic neurons, important for brain recovery.
- 5Study published in Nature Communications (DOI:10.1038/S41467-025-63725-3).
Why It Matters
The study demonstrates how AI-driven analysis can objectively measure neurological recovery in preclinical models, and highlights the translational potential of combining stem cell therapy and AI-based functional assessment for brain repair research.
Source
EurekAlert
Related News
•EurekAlert
Moffitt Develops AI Model to Predict Urgent Care in Lung Cancer Patients
Moffitt Cancer Center researchers created machine learning models that use patient-reported outcomes and wearable data to predict urgent care visits for non-small cell lung cancer patients.
•EurekAlert
AI Predicts Keratoconus Progression Using OCT Scans
Researchers have developed an AI model that accurately predicts which keratoconus patients require treatment by analyzing OCT eye scans and clinical data.
•EurekAlert
Mammogram-AI Accurately Predicts Women's Cardiovascular Disease Risk
AI analysis of mammogram images plus age predicts major cardiovascular disease risk as effectively as traditional tools.