Back to all papers

A Multi-phase CT Dataset for Automated Differential Diagnosis of Liver Tumors.

December 15, 2025pubmed logopapers

Authors

Wu XA,Su H,Hua Y,Xu Y,Wang L,Wang X,Wang S,Jin B,Liu X,Wan X,Sun Q,Wang X,Du S

Affiliations (10)

  • Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang Rd, Guangzhou, 510120, Guangdong Province, China.
  • School of Information Science and Technology, Fudan University, Shanghai, 200438, China.
  • Shanghai Artificial Intelligence Laboratory, Shanghai, China.
  • Shanghai Innovation Institute, Shanghai, 200231, China.
  • Department of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [email protected].
  • Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [email protected].
  • State Key Laboratory of Common Mechanism Research for Major Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [email protected].

Abstract

Liver tumors exhibit significant heterogeneity in etiology, pathology, and treatment response, making accurate differential diagnosis critical for diagnosis and management. While multi-phase contrast-enhanced computed tomography (CT) provides valuable imaging patterns for differentiation, visual assessment alone is often limited by overlapping features. To address this, we present MCT-LTDiag, a comprehensive Multi-phase CT dataset for Liver Tumor Diagnosis, comprising 517 cases with four-phase contrast-enhanced CT scans (non-contrast, arterial, portal venous, and delayed phases) and five tumor subtypes: hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), colorectal liver metastasis (CRLM), breast cancer liver metastasis (BCLM), and hepatic hemangioma (HH). The dataset features standardized preprocessing, rigorous quality control, and expert-annotated tumor masks. Baseline experiments using radiomics-based machine learning and deep learning models demonstrate the dataset's utility, with multi-phase integration significantly improving diagnostic performance. MCT-LTDiag serves as a benchmark for advancing automated liver tumor subtype classification and is publicly available to support future research.

Topics

Journal Article

Ready to Sharpen Your Edge?

Subscribe to join 7,200+ peers who rely on RadAI Slice. Get the essential weekly briefing that empowers you to navigate the future of radiology.

We respect your privacy. Unsubscribe at any time.