Seven commercial AI devices for lung cancer detection on chest x-rays show substantial and clinically meaningful performance variability.
Key Details
- 1Seven commercial AI tools were evaluated on 5,235 chest x-rays in a UK single-center study.
- 2Sensitivity ranged from 20.8% to 77.8%; specificity from 58.9% to 98.4%; positive predictive value from 1.5% to 28.4%.
- 3Significant differences were observed in 39 of 44 pairwise comparisons between devices.
- 4Three devices detected more tumors than radiologists; four detected fewer.
- 5False positives for tumor detection ranged widely (10 to 2,039 cases per device).
- 6Minimal agreement among devices (Fleiss κ = 0.24) highlights inconsistent results.
Why It Matters

Source
AuntMinnie
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