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MSK Research: Proton Therapy, AI Pain Summaries, and Tumor Metastasis Insights

EurekAlertResearch
MSK Research: Proton Therapy, AI Pain Summaries, and Tumor Metastasis Insights

MSK Cancer Center research advances include proton therapy for leptomeningeal metastasis and evaluating large language models for cancer pain summary.

Key Details

  • 1Proton therapy controls leptomeningeal metastasis, with patients living over twice as long versus conventional radiation.
  • 2Randomized phase 2 trial: proton craniospinal therapy offers stability >3x longer for LM compared to standard radiation.
  • 3Study funded by PCORI explores LLM-based PainReporter model to summarize cancer patient pain experiences from narrative notes.
  • 4Research on tumor genetics and location finds SMAD4 reactivation suppresses liver metastases but increases lung metastases.
  • 5Regulatory T cells, via enkephalin, regulate pain/inflammation in skin neuronal circuits.

Why It Matters

Advances in radiotherapeutic options like proton therapy improve outcomes in difficult cancer metastasis scenarios. Testing LLMs for summarising patient pain could impact clinical workflow, interpretation, and the integration of AI into patient care.

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