Large International Study: AI Boosts Prostate MRI Diagnostic Accuracy
June 13, 2025
AI assistance significantly improves radiologists' accuracy in detecting clinically significant prostate cancer on prostate MRI, according to a large international multi-reader study.
Key Details
- Study published June 13 in JAMA Network Open evaluating AI in prostate MRI diagnosis.
- 61 readers from 53 centers in 17 countries participated (34 experts, 27 nonexperts).
- AI assistance increased ROC AUC by 3.3% (from 0.882 to 0.916).
- Sensitivity improved by 2.5% (from 94.3% to 96.8%), specificity increased by 3.4% (from 46.7% to 50.1%).
- Nonexperts saw higher gains (sensitivity +3.7%) than experts (+1.5%).
- Readers used data from the PI-CAI Challenge; results suggest AI reduces interreader variability.
Why It Matters
This robust evidence supports the value of AI in improving prostate cancer detection on MRI, especially for less experienced readers, and reinforces ongoing efforts to integrate AI into clinical radiology workflows.