
Advanced imaging uncovers that glioblastoma affects the skull and immune system, not just the brain.
Key Details
- 1Montefiore Einstein researchers found glioblastoma erodes skull bones and alters skull marrow immune makeup.
- 2CT imaging of patients showed similar skull erosions as seen in mouse models with glioblastoma.
- 3Single-cell RNA sequencing revealed a shift toward pro-inflammatory immune cells in the skull marrow.
- 4FDA-approved osteoporosis drugs halted skull erosion but made tumors more aggressive and impaired immunotherapy effects.
- 5Findings suggest glioblastoma should be seen as a systemic, not just local, disease.
Why It Matters

Source
EurekAlert
Related News

Chinese Researchers Unveil Photonic Chip for Ultra-Fast Image Processing
A new photonic chip achieves image processing at 25 million frames per second with high energy efficiency, promising major advances in real-time imaging and AI applications.

AI Model Predicts Growth Spurts from Pediatric Neck X-rays for Orthodontics
Korean researchers developed an AI system (ARNet-v2) that predicts children's growth spurts from neck X-rays to enhance orthodontic treatment planning.

Dana-Farber Showcases AI and Clinical Trial Advances at ESMO 2025
Dana-Farber researchers present major cancer clinical trial results, including AI-driven data analysis, at ESMO Congress 2025.