A 'habitat' AI model outperforms standard 2D approaches in stratifying lung adenocarcinoma risk in subsolid nodules on low-dose CT scans.
Key Details
- 1The study evaluated a 'habitat' AI model, 2D model, radiomic model, and a combined model for classifying invasiveness and grade of lung adenocarcinoma presenting as subsolid nodules on LDCT.
- 2747 patients with 834 resected lung adenocarcinomas were included, split into training, internal, and external test sets.
- 3On the external test set, the macro-average AUCs were: 2D model 0.87, habitat model 0.92, radiomic model 0.92, and combined model 0.93.
- 4Habitat imaging quantifies spatial heterogeneity by segmenting nodules into subregions based on characteristics like signal intensity.
- 5Habitat and radiomic models both significantly outperformed the traditional 2D approach.
Why It Matters
Habitat AI models offer a novel, more accurate, and interpretable tool for noninvasive risk stratification of subsolid lung nodules, which could enhance early lung cancer screening workflows and reduce interobserver variability among radiologists.
Source
AuntMinnie
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