AI System Estimates Bone Mineral Density from X-rays, Improves Osteoporosis Detection

July 9, 2025

Researchers have developed an AI-based system to estimate bone mineral density from lumbar and femur X-rays for early osteoporosis detection.

Key Details

  • AI system analyzes lumbar spine and femur bone mineral density from X-ray images.
  • Study examined 1,454 X-ray images using the AI tool.
  • Sensitivity for detecting osteopenia: 86.4% (lumbar), 84.1% (femur).
  • Specificity for detecting osteopenia: 80.4% (lumbar), 76.3% (femur).
  • System also demonstrated high accuracy for detecting osteoporosis.
  • Potential for opportunistic and widespread clinical screening using routine X-rays.

Why It Matters

This AI system could enable more efficient and accessible osteoporosis screening by leveraging existing X-ray infrastructure, addressing unmet diagnostic needs globally and potentially reducing undiagnosed cases.

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