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AI Model Improves Prediction of Knee Osteoarthritis Progression Using MRI and Biomarkers

A new AI-assisted model that combines MRI, biochemical, and clinical data improves predictions of worsening knee osteoarthritis.
Key Details
- 1The AI model, LBTRBC-M, integrates MRI radiomics, biochemical, and clinical information.
- 2Study used data from 594 people with 1,753 knee MRIs over two years.
- 3Model accurately predicted pain worsening and joint space narrowing up to two years in advance.
- 4Resident physicians' prediction accuracy improved from 46.9% to 65.4% with model assistance.
- 5Findings published in PLOS Medicine; further validation needed in broader populations.
Why It Matters
This research demonstrates the potential for AI to combine imaging and non-imaging data, improving prognostic accuracy for musculoskeletal conditions. Such models could support earlier and more tailored interventions in knee osteoarthritis, directly enhancing radiological and clinical workflows.

Source
EurekAlert
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