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AI Knowledge Graph Boosts Decision Support in Recurrent Pregnancy Loss

EurekAlertResearch
AI Knowledge Graph Boosts Decision Support in Recurrent Pregnancy Loss

A novel graph-based AI system, RSA-KG, significantly improves clinical decision support for diagnosing recurrent spontaneous abortion (RSA) by integrating multimodal clinical data and expert guidelines.

Key Details

  • 1RSA-KG integrates structured and unstructured clinical data, including imaging reports, lab values, and molecular biomarkers.
  • 2The knowledge graph is built from five major international RSA guidelines and extensive literature using NLP and multimodal AI models.
  • 3A rigorous evaluation with 3,000 clinician-validated questions showed RSA-KG-enhanced LLMs outperform naive RAG and raw models (e.g., 86.5% vs. 76.5% accuracy for DeepSeek-R1).
  • 4Qualitative expert scoring from 10 clinicians confirmed higher clinical usefulness of RSA-KG outputs over standard LLMs and other medical models.
  • 5Key limitations include limited biomarker recency, single-discipline expert evaluation, and need for multicenter clinical validation.

Why It Matters

RSA-KG demonstrates a state-of-the-art integration of guidelines, imaging, and clinical data via AI, highlighting pathways to more adaptable and clinically relevant decision support systems in complex diagnostic areas. Radiology-AI professionals can leverage such frameworks for robust, multimodal reasoning and model validation.

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