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AI Enables Rapid Body Composition Analysis on Routine MRI to Predict Cardiometabolic Risk

EurekAlertResearch

An open-source AI tool can quickly and accurately assess body composition from routine MRI, helping identify patients at elevated cardiometabolic risk.

Key Details

  • 1Study analyzed 33,539 UK Biobank participants without prior diabetes, MI, or stroke using whole-body MRI.
  • 2Open-source AI model estimated subcutaneous/visceral adipose tissue, skeletal muscle volume, and fat fraction in under 3 minutes per scan.
  • 3AI-derived visceral fat and skeletal muscle fat fraction were independently associated with incident diabetes and major cardiovascular events over median 4.8 years follow-up.
  • 4Associations were adjusted for traditional risk factors, BMI, and waist circumference.
  • 5Visceral adipose tissue, but not subcutaneous fat, was a key predictor of future risk, corroborating previous findings.

Why It Matters

This work demonstrates the clinical utility and technical feasibility of using AI to extract prognostic body composition data from existing routine MRI scans, potentially enabling radiologists to flag high-risk patients for early intervention without workflow disruption.

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