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AI and fMRI Power Personalized TMS for Smoking Cessation at MUSC

EurekAlertResearch
AI and fMRI Power Personalized TMS for Smoking Cessation at MUSC

MUSC researchers used machine learning on fMRI scans to predict which smokers would benefit from repetitive transcranial magnetic stimulation (rTMS) for quitting smoking.

Key Details

  • 1MUSC study combines machine learning and fMRI to personalize rTMS for smoking cessation.
  • 242 participants took part in an earlier study, split into real vs sham TMS groups.
  • 3The salience network's connectivity in the brain, analyzed by AI, correlated best with positive rTMS outcomes.
  • 4Machine learning enabled predictions of individual responsiveness to rTMS based on brain network analysis.
  • 5Study published in Brain Connectivity; NIH grant support cited.
  • 6The research establishes groundwork for precision neuromodulation and larger future trials.

Why It Matters

This study demonstrates how imaging AI can enhance precision medicine by analyzing fMRI scans to tailor neuromodulation therapies. The approach could extend to other substance use disorders, highlighting a broader potential impact for radiology-based AI tools.

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